Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Diagnosis: Latent ... Treatment: Active ... Initiating Treatment ... #TB #Diagnosis ... #Management #Treatment
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
TB • LTBI is diagnosed ... infection • Recent ... viral infections ... used to exclude pulmonary ... LatentTB #ActiveTB #InfectiousDiseases
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Diagnosis: Latent ... Treatment: Active ... Initiating Treatment ... #TB #Diagnosis ... #Management #Treatment
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... : • helminth infections ... • Tuberculosis ... #Differential #Diagnosis ... #causes #hematology
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
- Differential Diagnosis ... effusion/Tamponade Hematologic ... dysfunction; toxic ingestions ... #Differential #Diagnosis ... #pulmonary
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... Etiology: - Infections ... Solid Tumors • Tuberculosis ... NonHodgkins #comparison #oncology ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... - Syphilis - Tuberculosis ... Knee #Effusions #causes ... #differential #diagnosis
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Chronic inflammation causes ... Most Common Causes ... parenchyma Diagnosis ... mycobacteria Treatment ... #differential #diagnosis
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... status NTM Cause ... Hematologic malignancy ... patients with typical tuberculosis ... #infectiousdiseases
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... 80% sensitive Tuberculous ... - Hemorrhage, tuberculomas ... Demyelinating disease caused ... opportunistic #InfectiousDiseases