jake @Jmarasco
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Amenorrhea - Differential Diagnosis Algorithm
Elevated FSH
 • Premature Ovarian Failure
 • Menopa use
 • Spontaneous
Bleed With
Challenge • Hypothyroidism ... • Hyperthyroidism ... Hyperprolactinemia Organic Cause ... Challenge • Functional ... endocrinology #causes
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... Secondary hyperthyroidism ... Pretibial myxedema #Primary ... #Hyperthyroidism ... endocrinology #pathophysiology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... structure-related • Primary ... Parathyroid gland function-related ... vitamin A intake • Hyperthyroidism ... Hypercalcemia #Causes
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm
No onset of menarche by age 16 with secondary
Causes of Primary ... Hypothalamic: • Functional ... Hyperprolactinemia • Hypothyroidism ... #Primary #Amenorrhea ... Diagnosis #Algorithm #Causes
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... hypotension - Nausea ... eosinophilia Primary ... - Secondary hypothyroidism
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Endocrinopathies - Hypothyroidism ... renal failure - Primary ... Diagnosis #Table #Causes
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... decr eiection fraction ... endocrinology #pathophysiology
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm
Absence of menses for more than 3 cycles or
Causes of Secondary ... estrogen: • Functional ... compression) • Hypothyroidism ... Diagnosis #Algorithm #Causes