Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... hepatitis - Acute biliary ... Hemochromatosis - Primary ... biliary cholangitis ... Severe #Acute #Causes
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... with PBC #PBC #Primary ... #Biliary #Cirrhosis ... #Diagnosis #Algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... obstruction, Primary ... biliary cholangitis ... , Primary sclerosing
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... indicate the initial evaluation ... history alongside evaluation ... include extrahepatic biliary ... #Algorithm #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
congenital - Primary ... biliary cirrhosis ... Hepatology #Cirrhosis #Causes
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Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm

#Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... PBC) - Diagnosis Algorithm ... #Primary #Biliary ... PBC #Diagnosis #Algorithm
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... , further evaluation ... C282Y homozygote, evaluation ... hemochromatosis #algorithm
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
Algorithm for the ... Diagnosis of Primary ... Biliary Cholangitis ... antibodies #Primary ... #PBC #Algorithm
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... 1.5x ULN and/or abnormal ... disease #PBC #Primary ... #Biliary #Cirrhosis
Rome IV Criteria for diagnosing Functional Abdominal Pain Disorders (FAPD)
Irritable bowel syndrome
The criteria must be fulfilled
After appropriate evaluation ... After appropriate evaluation ... interferes with normal ... following: anorexia, nausea ... After appropriate evaluation