Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Autoimmune ... cholangitis ... Acute #Causes #Differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... dose, duration), Several ... cholangitis, Primary ... steatosis • Autoimmune ... hepatitis #DILI
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... Schistosomiasis - Autoimmune ... congenital - Primary biliary ... Nonalcoholic fatty liver ... #Diagnosis #Differential
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Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... of associated autoimmune ... Liver biopsy findings ... #PBC #Primary #Biliary
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... day) survival in severe ... can be bridge to Liver ... #Management #Algorithm
Autoimmune Hepatitis (AIH) Management Algorithm - Induction and Maintenance
 - AIH
 - AIH with Cirrhosis
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Autoimmune Hepatitis ... AIH) Management Algorithm ... Cirrhosis - Acute Severe ... AIH #Autoimmune ... #Hepatitis #AIH
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... include extrahepatic biliary ... LFTs #Abnormal #Algorithm ... #Enzymes #Differential