Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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diagnosis hepatology differential cirrhosis gastroenterology liver pbc primary abnormal acute dili druginduced dyspepsia enzymes functional gallstone hemochromatosis injury lfts liverinjury
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... female-predominant disease ... of autoimmune disease ... #PBC #Primary #Biliary
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... hepatitis - Acute biliary ... hepatitis - Wilson disease ... Hemochromatosis - Primary biliary ... Severe #Acute #Causes
Gallstone Diseases 1. Asymptomatic Stones 75% 2. Biliary Pain 20% 3. Acute Cholecystitis 10% 4. Mirizzi's Syndrome < 0.1% 5. Cholangitis/
Gallstone Diseases ... Biliary Pain 20% ... #Gallstone #Diseases ... differential #diagnosis #causes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
congenital - Primary biliary ... Nonalcoholic fatty liver disease ... - Wilson disease ... Venoocclusive disease ... Hepatology #Cirrhosis #Causes
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 Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... associated autoimmune disease ... of autoimmune disease ... #PBC #Primary #Biliary
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Alcohol-related liver disease ... Benign/malignant biliary ... obstruction, Primary biliary
Functional Dyspepsia - Signs, Symptoms and Pathophysiology Delayed gastric emptying - Postprandial fullness, nausea, vomiting Hypersensitivity to gastric
, Symptoms and Pathophysiology ... hypersensitivity - Nausea ... hypersensitivity - Nausea ... nonerosive reflux disease ... Functional #Dyspepsia #Pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... include extrahepatic biliary ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... LFTs #Abnormal #Algorithm
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... out additional causes ... of liver disease ... If other causes ... hemochromatosis #algorithm
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