Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
hepatitis - Acute biliary ... Hemochromatosis - Primary biliary ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
congenital - Primary biliary ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
include extrahepatic biliary ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... inflammation and biliary ... #PBC #Primary #Biliary ... Pathophysiology #hepatology
Portal Hypertension Differential

#Diagnosis #Hepatology #Differential #PortalHypertension #PortalHTN #Prehepatic #Posthepatic #Intrahepatic
Portal Hypertension Differential ... #Diagnosis #Hepatology ... #Differential #
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... #PBC #Primary #Biliary ... Diagnosis #Algorithm #hepatology
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Biliary Pain 20% ... Gallstone #Diseases #differential
An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
to Jaundice - Differential ... #Jaundice #Differential ... Posthepatic #Diagnosis #Hepatology
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
#Medications #Differential ... #LiverInjury #Hepatology
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Injury #Diagnosis #Hepatology ... Injury #Causes #Differential