Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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hepatology diagnosis primary algorithm causes management treatment abnormal diseases enzymes gallstone hbv hepatitisb hepbv indications lfts liver liverinjury pathophysiology severe
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... consistent with PBC ... #PBC #Primary ... #Biliary #Cirrhosis
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... relative with PBC ... Cholestasis #PBC ... #Cirrhosis #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm #Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... Cirrhosis (PBC) ... Algorithm #Primary #Biliary ... #Cirrhosis #PBC
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe Acute ... hepatitis - Acute ... biliary obstruction ... Hemochromatosis - Primary biliary ... #Causes #Differential
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary biliary ... cirrhosis - α1 ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
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 Gallstone Diseases 1. Asymptomatic Stones 75% 2. Biliary Pain 20% 3. Acute Cholecystitis 10% 4. Mirizzi's Syndrome < 0.1% 5. Cholangitis/
Biliary Pain 20% ... Acute Cholecystitis ... Gallstone #Diseases #differential
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... immunosuppression • Acute ... > 3 mg/dL) or acute
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... survey disease #PBC ... #Primary #Biliary ... #Cirrhosis #Management
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
include extrahepatic biliary ... body mass index; FBC ... Liver #Enzymes #Differential
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