Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... hepatitis - Acute ... hepatitis - Wilson disease ... #Causes #Differential
Functional Dyspepsia - Pathophysiology, Diagnosis and Management
Risk factors: Non-steroidal anti-inflammatory drugs, Psychological comorbidity, Helicobacter pylori infection,
Functional Dyspepsia ... pylori infection, Acute ... Early satiety #Functional ... Diagnosis #Management #algorithm
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Gallstone Diseases ... Acute Cholecystitis ... #Gallstone #Diseases ... differential #diagnosis #causes
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
and Management Algorithm ... factors: Previous acute ... Younger age, Other functional ... common: Food, Acute ... Diagnosis #Management #Algorithm
Functional Dyspepsia - Signs, Symptoms and Pathophysiology
Delayed gastric emptying - Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric
Functional Dyspepsia ... hypersensitivity - Nausea ... hypersensitivity - Nausea ... nonerosive reflux disease ... Epigastric pain #Functional
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Alcohol-related liver disease ... dechallenge • Acute ... Injury #Diagnosis #Algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... LFTs #Abnormal #Algorithm
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... out additional causes ... of liver disease ... If other causes ... hemochromatosis #algorithm
Causes of a low fecal elastase
Abnormal pancreatic imaging:
Chronic pancreatitis, Pancreatic tumours including cystic disease, Pancreatic resection,
Causes of a low ... including cystic disease ... Pancreatic atrophy, Acute ... pancreas), Genetic causes ... differential #diagnosis #causes
Rome IV Criteria for diagnosing Functional Abdominal Pain Disorders (FAPD)
Irritable bowel syndrome
The criteria must be fulfilled
for diagnosing Functional ... resolves have functional ... medical condition Functional ... episodes of intense, acute ... following: anorexia, nausea