Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... #Medications #Differential ... #LiverInjury #Hepatology ... #Pharmacology #Causes
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... hepatitis - Wilson disease ... Severe #Acute #Causes ... #Differential # ... Hepatology #Diagnosis
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
- Wilson disease ... Venoocclusive disease ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... Injury #Diagnosis #Hepatology ... Liver #Injury #Causes ... #Differential #
An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
to Jaundice - Differential ... #Jaundice #Differential ... #Table #Causes ... Posthepatic #Diagnosis #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Cirrhosis - Diagnosis Algorithm ... associated autoimmune disease ... of autoimmune disease ... Cirrhosis #Diagnosis #Algorithm ... #hepatology
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Gallstone Diseases ... #Gallstone #Diseases ... #differential # ... diagnosis #causes
Gastrointestinal Causes of Iron Deficiency Anemia
 • Mass lesions: Carcinoma, Large polyps
 • Inflammatory: Reflux esophagitis,
Gastrointestinal Causes ... sprue, Whipple's disease ... ulcers, Crohn's disease ... Deficiency #Anemia #Causes ... #differential #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Alcohol-related liver disease ... Injury #Diagnosis #Algorithm ... #hepatology
Causes of Small Bowel Bleeding - Differential Diagnosis
Common Causes:
 • Under age 40 years: Inflammatory Bowel
Causes of Small ... Bowel Bleeding - Differential ... Diagnosis Common Causes ... Inflammatory Bowel Disease ... SmallBowel #Bleeding #Differential