Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Cholestasis #PBC #Primary ... #Biliary #Cirrhosis ... #Pathophysiology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... with PBC #PBC #Primary ... #Biliary #Cirrhosis
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary ... biliary cirrhosis ... Differential #Hepatology #Cirrhosis
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Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm

#Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... Cirrhosis (PBC) ... Algorithm #Primary ... #Biliary #Cirrhosis
Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
Cirrhosis - Pathophysiology ... Infections #Cirrhosis ... #Pathophysiology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
hepatitis - Acute biliary ... Hemochromatosis - Primary ... biliary cholangitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Benign/malignant biliary ... obstruction, Primary ... biliary cholangitis ... , Primary sclerosing
A cirrhosis tweetorial all about the platelet

Aims:
- Identify cirrhosis based on blood tests- 
- Understand why
A cirrhosis tweetorial ... Aims: - Identify cirrhosis ... platelets are low in #cirrhosis ... s role in the #cirrhotic ... Tweetorial #Hepatology #Pathophysiology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Liver Consult Primer ... Gl History - Cirrhosis ... Consultation #GIConsult #Primer
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... disease #PBC #Primary ... #Biliary #Cirrhosis