Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
Cirrhosis - Pathophysiology ... Infections #Cirrhosis ... #Pathophysiology ... #hepatology #liver
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Primary biliary cirrhosis ... Nonalcoholic fatty liver
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... mg/dL) or acute liver ... failure #HepatitisB
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... paracentesis (>5 liter ... ) - 8g per liter ... Indications #Management #Cirrhosis ... #treatment #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... Alcohol-related liver ... ascites), Chronic hepatitis ... • Autoimmune hepatitis
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... can be bridge to Liver ... #Alcoholic #Hepatitis ... Management #Algorithm #treatment
Nutrition in Cirrhosis: Dos and Don’ts
Screening:
 • Patients at risk for RFH-Nutritional Prioritizing Tool
 • Low
Nutrition in Cirrhosis ... ) • Advanced liver ... cirrhosis. ... #Nutrition #Cirrhosis ... management #hepatology #pathophysiology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... symptoms, elevated liver ... is >1,000 μg/L, liver ... Patients with cirrhosis ... A liver biopsy can
Autoimmune Hepatitis (AIH) Management Algorithm - Induction and Maintenance
 - AIH
 - AIH with Cirrhosis
 -
Autoimmune Hepatitis ... AIH - AIH with Cirrhosis ... #Autoimmune #Hepatitis ... Management #Algorithm #treatment