Dean Ehrlich @DeanEhrlich_MD
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Chief Fellow #UCLAGI @uclabiodesign Fellow, Former Chief Res @uclaimchiefs https://twitter.com/DeanEhrlich_MD #Endoscopy, #Innovation, #MedTech, #MedEd
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gastroenterology management diagnosis syndromes colorectal polyposis adenomatous colon hamartomatous inherited intervals lynch polyp screening surveillance syndrome
Inherited Colorectal Cancer (CRS) Syndromes Adenomatous Polyposis Syndromes: • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Inherited Colorectal Cancer ... (CRS) Syndromes ... Syndrome: • "CRC ... Inherited #Colorectal #Cancer ... #CRS #Syndromes
Colorectal Cancer Screening and Polyp Surveillance Intervals Colon Cancer Screening - Modality - Interval: • Colonoscopy -
Colorectal Cancer ... Intervals Colon Cancer ... Colorectal #colon #Cancer
Lynch Syndrome: • "CRC + Endometrial/Ovarian + Stomach + Urinary → Lynch Syndrome" • Autosomal Dominant,
Syndrome: • "CRC
Hamartomatous Polyposis Syndromes - Peutz-Jeghers Syndrome (PJS), Juvenile Polyposis Syndrome (JPS), Cowden Syndrome (CS), Cronkhite-Canada (CC),
Cowden Syndrome (CS ... Hamartomas + GI Cancer ... → Adenoma and cancer ... Cowden Syndrome (CS ... Likely risk of CRC
Adenomatous Polyposis Syndromes: Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH associated polyposis (MAP) ✓ Genetic
Polyposis (FAP): - "CRC ... adenomas → 100% CRC ... have > 100 - CRC ... Slight ↑ CRC) →
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