92 results
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory Syndrome ... Kawasaki Disease CDC ... hospitalization • >2 ... diagnosis #peds #pediatrics ... #Inflammatory #Syndrome
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... disomy: inheriting 2 ... Obesity -> Type 2 ... #genetics #pathophysiology ... #peds #pediatrics
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... with SARS-CoV-2 ... neck swelling #Pediatrics ... #Inflammatory #Syndrome
Tetralogy of Fallot Summary
 • Anatomy
 • Incidence
 • Pathophysiology
 • Presentation
 • Common Variants
 •
• Incidence • Pathophysiology ... Associated Genetic Syndromes ... cardiology #peds #pediatrics
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... synthesis - IL-2 ... Basiliximab - IL-2 ... Suppression of IL-2 ... #Pharmacology #Pathophysiology
Common Childhood Exanthems - Differential Diagnosis
1) Rubeola (Measles) - Measles morbillivirus (MeV)
2) Scarlet Fever - Streptococcus
morbillivirus (MeV) 2) ... Staphylococcal Scalded Skin Syndrome ... Differential #Diagnosis #pediatrics
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... DRESS • Latency: 2- ... with erosions • CBC ... with bleeding at 2 ... SCVMCMed #DRESS #Syndrome
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Presenilin 1 and 2 ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Management of Necrotizing Pancreatitis

Severe Pancreatitis
Pathophysiology
Diagnosis of Pancreatic Necrosis
Infected Necrosis
Complications of Severe Pancreatitis: 
1) Pancreatic Fistula
2) Disconnected
Pancreatitis Pathophysiology ... Pancreatic Fistula 2) ... Pancreatic Duct Syndrome
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Human Stages: 2) ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc