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diagnosis hematology management differential workup adult autoimmune biliary chronic classification cll hemeonc hemophagocytic hepatology hlh incomplete kawasaki leukemia lymphocytic lymphohistiocytosis
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... Symptoms: Fatigue ... quadrant discomfort Signs ... if 2/3 criteria
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... internal organs 3 ... and Symptoms: ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... if evidence of systemic ... purposes of this algorithm ... clinical and lab signs ... #Incomplete #Algorithm
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Systemic inflammation ... the chest/trunk Symptoms ... weeks or longer 3. ... #AOSD #diagnosis ... #rheumatology #
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Summary Diagnostic Criteria ... incidentally via CBC ... , signs, and complications ... • Treatment algorithms ... von Willebrand disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
or proteinase 3 ... Symptoms (Sx) in ... purpura: strong sign ... are proteinase 3 ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3.
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... : • PBC, autoimmune
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... ▪ Autoimmune diseases ... Activation Syndrome) 3. ... Presentation • Common Signs ... and Symptoms:
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