27 results
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Still's disease ... 3. ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... internal organs 3 ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... criteria are met ... gp210/sp100) 3. ... Diagnosis #Algorithm #hepatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Lung involvement 3% ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... Signs and symptoms ... McDonald diagnostic criteria ... for MS 3.
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Symptoms (DRESS ... Criteria for Diagnosis ... different areas 3. ... Resolution > 15 days Differentials
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
or proteinase 3 ... Symptoms (Sx) in ... purpura: strong sign ... are proteinase 3 ... #diagnosis #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... Systemic inflammation ... the chest/trunk Symptoms ... weeks or longer 3. ... AOSD #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
3 Types of Cold ... Antibodies[PCH] 3. ... (Cold-induced symptoms ... younger pts) Differential ... hemolytic #anemia #hematology