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diagnosis differential management rheumatology vasculitis algorithm als amyotrophic arteritis autoantibodies causes central classification cord disorders erythematosus gca giantcell lateral lupus
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... internal organs 3 ... skin thickening Signs ... and Symptoms: ... rheumatology #diagnosis #signs
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Lung involvement 3% ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
fifth decades. 3. ... with significant neurologic ... weeks to months. 3. ... Multiple sclerosis ... signs or symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... , Aspergillus 3. ... , Scleroderma, Systemic ... sclerosis - MCTD ... disorders #diagnosis #neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... sx + signs/sx of ... elicited after 2-3 ... slow taper over 1-3 ... GCA #Temporal #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
or proteinase 3 ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... are proteinase 3
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... suggestive of multiple sclerosis ... : - Multiple sclerosis ... diagnosis #management #neurology
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