8 results
diagnosis hematology oncology hemophagocytic hlh lymphohistiocytosis apml arteritis autoimmune classification differentiation gca giantcell hemeonc hodgkins leukemia lymphocytic lymphoma myopathy myositis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... Physical Exam/Signs ... Agranulocytosis 3. ... Elevated LDH 5.
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... Diagnosis: HLH signs ... and symptoms can ... Low or absent NK cell ... Lymphohistiocytosis #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... if WBC > 5 or elevated ... symptoms, or> 1 ... initiation • Differential ... APML #diagnosis #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... elicited after 2-3 ... them, but urgent rheumatology ... #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... • Progressive symptoms ... or proteinase 3 ... Eosinophilia, asthma, chronic ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... in 1/3 of patients ... Inflammatory marker elevated ... Immunohistochemical studies (to differentiate ... #oncology #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... papules and Gottron sign ... ) • Shawl sign ... kinase levels are elevated ... #differential #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Activation Syndrome) 3. ... Presentation • Common Signs ... and Symptoms: ... Elevated soluble ... #Hematology #HemeOnc
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