21 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... • Meningeal signs ... ) • Systemic symptoms ... and signs (e.g. ... #neurology #PHANTOMS
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... test - Cogan sign ... - Peek sign
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
fifth decades. 3. ... (Wallenberg's syndrome ... weeks to months. 3. ... Syndrome usually ... signs or symptoms
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Neuroleptic malignant syndrome ... hyperthermia crisis (late sign ... syndrome (cocaine ... Anticholinergic syndrome ... Sympathomimetic syndrome
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... Episcleritis Signs ... classical Sweet syndrome ... - Schnitzler’s syndrome
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... diagnosis #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... affects infants < 3 ... Diagnosis: HLH signs ... and symptoms can ... #hematology