45 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... common primary disease ... Manifestations #Disease ... Systems #Diagnosis #Hematology ... #Signs #Symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... involvement (type 2 and 3) ... #Gauchers #Disease ... #Diagnosis #Signs ... #Symptoms
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... Diagnose PBC if 2/3 ... gp210/sp100) 3.
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
spontaneous within 3- ... 6 months of symptom ... intervertebral disc disease ... differential #diagnosis #signs ... #symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... distribution of nearly 3: ... Signs and symptoms ... 1000 mg daily 3- ... an oral taper 3-
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
fifth decades. 3. ... Méniére's disease ... weeks to months. 3. ... Disease onset usually ... varying neurologic signs
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's Disease ... Lymphoma Metastatic Disease ... vomiting • Fatigue Signs ... Reduced libido • Signs ... Serum cortisol < 3
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... internal organs 3 ... skin thickening Signs ... and Symptoms: ... #symptoms #testing
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
3 Types of Cold ... Antibodies[PCH] 3. ... (Cold-induced symptoms ... rewarming • Symptoms ... hemolytic #anemia #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... Cryoglobulinemia vasculitis (3% ... Vasculitis #dermpath #dermatology ... #semiology #signs