12 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Sarcoidosis Non-caseating ... Clinical: • Disease ... polyarthritis • Pulmonary ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Sarcoidosis
Stage 1 - Bilateral LAD without involvement of lung parenchyma
Stage 2 - Bilateral LAD with involvement
Sarcoidosis Stage ... parenchyma Stage 3 ... interstitial lung disease ... Stages #Staging #Signs ... #Symptoms #Summary
Hilar and mediastinal lymphadenopathy
In sarcoidosis the common pattern is right paratracheal and bilateral hilar adenopathy ('1-2-3-sign').
In
lymphadenopathy In sarcoidosis ... adenopathy ('1-2-3- ... sign'). ... postirradiation Hodgkin disease ... Diagnosis #Radiology #Pulmonary
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
internal organs 3 ... skin thickening Signs ... and Symptoms: ... ), PAH (pulmonary ... rheumatology #diagnosis #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
patients have no symptoms ... Pulmonary: dyspnea ... Pulmonary and ... Diagnosis #Management #Signs ... #Symptoms
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... Serum cortisol < 3 ... endocrinology #diagnosis #signs
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
caucasian • Symptoms ... visual loss (avg. 3/ ... Unilateral • Signs ... indicated if NMOSD or sarcoidosis ... other auto-immune diseases
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Neuromyelitis optica - Sarcoidosis ... , Aspergillus 3. ... Inflammatory: - Sarcoidosis ... , Behcet disease
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Connective tissue diseases ... Digital clubbing (2-3% ... Nasal polyps and signs ... , in advanced disease
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... or proteinase 3 ... Presentation - Systemic Symptoms ... purpura: strong sign ... are proteinase 3