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differential rheumatology classification causes chronic dermatology renal antibodies nephrology pulmonary vasculitides algorithm amyloid amyloidosis ana anca antibody antineutrophil antinuclear associations
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
granulomatosis - microscopic ... Churg-Strauss syndrome ... - Sjögren syndrome ... #Vessels #Diagnosis ... #Rheumatology #Diagnosis
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... retroorbital mass) • Microscopic ... Interstitial lung disease ... and Sjogren's syndrome ... #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... #diagnosis #table
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... #differential #diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... - Alport syndrome ... of GN or vasculitis ... of glomerular disease
Chronic Diarrhea - Differential Diagnosis Algorithm Steatorrhea - Maldigestive • Pancreatic Insufficiency - Primary
Chronic Diarrhea ... - Differential Diagnosis ... Irritable Bowel Syndrome ... Cancer • Microscopic ... Lymphoma #Chronic #Diarrhea
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential Diagnosis ... Associated: - Microscopic ... : • Behcet Disease ... • Cogan syndrome ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... PR3-ANCA): • Microscopic ... : • Behçet Syndrome ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... ANCA-Associated Vasculitis ... : • Microscopic ... Renal-limited vasculitis ... Antineutrophil #antibodies #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... : Vasculitis: ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... dermatology #rash #diagnosis
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