36 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... → Diagnostic of ... GN or vasculitis ... of glomerular disease
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
granulomatosis - microscopic ... Churg-Strauss syndrome ... - Sjögren syndrome ... #Vessels #Diagnosis ... #Rheumatology #Diagnosis
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... retroorbital mass) • Microscopic ... Interstitial lung disease ... and Sjogren's syndrome ... #diagnosis
Causes of Hemoptysis - Differential Diagnosis Algorithm
Massive Hemoptysis (>I00 mL in 24 hours)
 • Malignancy
 •
Causes of Hemoptysis ... Algorithm Massive ... Goodpasture's Syndrome ... polyangiitis / microscopic ... #Algorithm #Causes
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Algorithm Red ... cells on urine microscopy ... with polyangiitis/microscopic ... #Algorithm #Causes
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... #diagnosis #table
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... PR3-ANCA): • Microscopic ... tract, and often causes ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... Associated: - Microscopic ... : • Behcet Disease ... • Cogan syndrome ... #differential #diagnosis
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urinalysis/microscopy ... - Pre-renal disease ... Glomerulonephritis or vasculitis ... AKI #Nephrology #Diagnosis ... #Algorithm #Causes