8 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
(Antineutrophil ... • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... #Antineutrophil
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis (Eosinophilic ... polyangiitis, Microscopic ... vasculitis (IgA-associated ... vasculitis, Behcet ... testing: anti-ANCA
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... ): • Microscopic ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain hematuria syndrome ... hematuria: - RBC casts ... Diagnostic of GN or vasculitis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... Abdominal compartment syndrome ... syndrome: troponin
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... polyangiitis), MPA (microscopic ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... 20% Sjögren's syndrome ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... Mucocutaneous lymph node syndrome ... )): Microscopic ... • Behcet syndrome ... • Cogan syndrome