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diagnosis differential nephrology hematology syndromes vasculitis acute aki algorithm ana anca antibodies antibody antineutrophil antinuclear bloodsmear borrelia classification clinical dermatologic
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine • 1ml blood ... urine sediment Microscopic ... hematuria: - RBC casts ... microscopic and ... #urine #blood
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Investigations: full blood ... dipstick, urine microscopy ... osmolarity If cause ... syndrome: troponin
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Differential #Microscopy
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age • 22 and 45 cases ... abnormal under a microscope ... Workup: • Complete ... #diagnosis #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... antibodies #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... mononeuritis multiplex WORKUP ... reveals increasing blood ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... of Peripheral blood ... hematuria (without casts ... the presence of renal ... #Hematology
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Northeast Africa with cases ... Several cases have ... Syndrome: 3d of ... recurrentis #BloodSmear #microscopy
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... PR3-ANCA): • Microscopic ... tract, and often causes ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
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