31 results
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
granulomatosis - microscopic ... Churg-Strauss syndrome ... - Goodpasture syndrome ... - Schnitzler syndrome ... - Sjögren syndrome
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... Light Microscopy ... Haemolytic-uraemic syndrome ... Nephrotic syndrome ... #nephrology #pathology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Microscopic polyangiitis ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... retroorbital mass) • Microscopic ... Interstitial lung disease ... and Sjogren's syndrome ... • IgA vasculitis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... polyangiitis, Microscopic ... Infection, Alport Syndrome ... Pulmonary #Renal #Syndrome
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Alport syndrome ... pain hematuria syndrome ... Diagnostic of GN or vasculitis ... • Nutcracker syndrome ... causes #urology #nephrology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vasculitis Involving ... Associated: - Microscopic ... : • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and Disease ... Advanced kidney disease ... Red blood cell ... Fatty - Nephrotic syndrome ... #Differential #Microscopy
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
cases • Sjögren syndrome ... ANCA-Associated Vasculitis ... : • Microscopic ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology