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ana antibodies anca antibody antineutrophil arthritis autoantibodies bloodsmear borrelia classification cryoglobulinemia cryoglobulins dermatologic dermatology differential disease diseases erythematosus gpa granulomatosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... cases • Sjögren syndrome ... Vasculitis: • Microscopic ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence microscopy ... likely it will be clinically ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with MCTD and Raynaud's ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... Labs/Diagnosis: ... vasculitis - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis ... classification #rheumatology
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Syndrome: 3d of ... LBRF can be diagnosed ... recurrentis #BloodSmear #microscopy ... #pathology #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Differential Diagnosis ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... ab • RF • Antinuclear ... salivary ducts Clinical ... Cryoglobulinemia (4%-12%), Raynaud ... #Rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... erythematosus (SLE) - Antinuclear ... ANA and RF (if clinical ... #testing #Rheumatology
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