72 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Acquired Aplastic ... BoneMarrow #Failure #Aplastic ... #anemia #diagnosis ... #Hematology
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... vs Hypocellular MDS ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis ... #oncology #hematololgy
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Can progress to MDS ... #Anemia #diagnosis ... management #treatment #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
- Differential Diagnosis ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Deficiency • MDS ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential Diagnosis ... Non-hemolytic: ACD, Aplastic ... Non-megaloblastic: Liver disease ... Reticulocytosis, MDS ... #hematology
Pathophysiology, Signs and Symptoms of Hemolytic Anemia

#Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, Signs ... Symptoms of Hemolytic Anemia ... Pathophysiology #Hemolytic #Anemia ... #hematology #diagnosis ... #signs #symptoms
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Algorithm Signs ... #Differential #Diagnosis ... #Algorithm #hematology
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
, Hemolytic anemia ... : Hemoglobin H disease ... , Sickle cell, MDS ... Inclusions #Bodies #diagnosis ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Metastatic Disease ... #Algorithm #Hematology