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hematology diagnosis oncology management mds treatment algorithm autoinflammatory cancer chronic e1 leukemia lymphocytic myelodysplasia rheumatology somatic syndromes vacuoles vexas workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... count (anemia) ... platelets) • MDS ... precursors MDS ... • Aplastic Anemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #Syndrome #MDS
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Constitutional Syndromes ... • Hypocellular myelodysplastic ... syndrome (MDS)
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Consider stem cell ... Can progress to MDS ... Medicine @SCVMCMed #Aplastic
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... multiple myeloma, myelodysplastic ... syndrome (MDS) ... syndrome (MDS) ... (12%) • giant cell
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... aplasia • ITP ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic ... syndromes current ... 24 May 2018 Myelodysplastic ... syndromes (MDS) ... disease tolerate anemia
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