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diagnosis hematology management oncology aplastic chronic cll leukemia lymphocytic myelodysplastic cell classification hemeonc hodgkins lymphoma myelodysplasia neurology palsy plasmacytoma polycythemiavera
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... Pancytopenia: • ↓ RBC ... Treatment:
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Treatment: • Consider ... Can progress to MDS ... diagnosis #management #treatment ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... formed or don’t work ... platelets) • MDS ... precursors MDS ... chemotherapy #MDS
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
incidentally via CBC ... present, symptoms, signs ... transformation into AML or MDS ... • Treatment is ... #hematology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... progression: over 1-3d ... ophthalmoplegia), systemic signs ... No additional workup ... Diagnosis #Management #Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Lymphocytosis on CBC ... • Neutropenia, anemia ... microglobulin Treatment ... Leukemia #diagnosis #workup
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... marrow failure with anemia ... Lauren Banaszak, MD
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC ... Hodgkin Lymphoma Treatment
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... • CBC + diff • ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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