32 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
on Smear • Chronic ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... Disorder • RBC
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... parasitemia - normocytic RBCs ... multiples per RBC ... rare in blood smears ... Falciparum #Blood #Smear
Red Blood Cell Morphology Atlas

Size variation, Hemoglobin distribution,  
Hypochromia,  
Shape variation,  
Inclusions, 
Red
#Path #Blood #Smear ... #RBC #Morphology
Plasmodium - Identification Algorithm
 • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
rings, <1/3 size RBC ... Multiple rings/RBC ... rings, ≤ 1/3 size RBC ... trophs, >1/3 size RBC ... Algorithm #pathology #smear
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
Peripheral Blood Smear ... parasites per RBC ... peripheral #blood #smear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... Peripheral Blood Smear ... ↑ abnormal RBCs
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... #Path #Blood #Smear ... #Microscopy #RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... #Path #Blood #Smear ... #Microscopy #RBC
Case of Fitz-Hugh-Curtis (FHC) on CT

28F +4d RUQ pain worse w/ inspiration, 102F fever, no vaginal
Fitz-Hugh-Curtis (FHC ... on CT 28F +4d ... WBC 7, AST/ALT mildly ... FitzHughCurtis #FHC
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC