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Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Marrow Failure Syndromes ... Acquired Aplastic Anemia ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... (MDS) (normal or
Functional Dyspepsia Syndromes - Epigastric Pain Syndrome (EPS) and Postprandial Distress Syndrome (PDS) Epigastric Pain Syndrome (EPS): ≥
Epigastric Pain Syndrome ... (PDS) Epigastric ... Pain Syndrome ( ... (PDS) ≥1 of: ... Dyspepsia #EPS #PDS
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... #Aplastic #Anemia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... Deficiency • MDS ... #Macrocytic #Anemia
Trachea Hypermobility in Ehlers-Danlos Syndrome (EDS) #Trachea #Hypermobility #Ehlers #Danlos #Syndrome #EDS #clinical #video #physicalexam
Ehlers-Danlos Syndrome ... (EDS) #Trachea ... Ehlers #Danlos #Syndrome ... #EDS #clinical
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 Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
Differential Diagnosis of Anemias ... Diagnosis #IM #Honc #Anemia
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... Abnormalities: macrocytic anemia ... myelodysplastic syndrome ... (MDS) Most met ... (MDS) and/or
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Chronic disease anemia ... Sideroblastic anemia ... Liver Disease, MDS ... iron deficiency anemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #MDS #Diagnosis
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