8 results
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Disorder (HAND) ... CNS in the early stages ... : • Increased CSF ... #dementia #AIDS ... #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... Antimicrobial treatment ... Suspect in movement disorders ... altered mental status ... , and focal neurologic
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... • Weakness: Starts ... GQ1b IgG Antibody associated ... Treatment: • Plasmapheresis ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... fluctuations PRES-Associated ... epilepticus Treatment ... underlying cause • Treatment ... Seizures: Treat with AEDs
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
men • Commonly associated ... Pathophysiology: • Associated ... • CSF: Oligoclonal ... limb or joint disorders ... #neurology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Loop Diuretics; High-Ceiling ... specific bleeding disorders ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
iron overload states ... yeast • At risk: AIDS ... MC: CNS CSF: • ... change in the lungs ... nails, bronchi, lungs
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
Opioid Use Disorder ... intrinsic activity, high ... depression at certain stages ... been associated ... Comparison #Table #Pharmacology