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diagnosis hematology neurology aflp aids ammonia associated biliary cholangitis cirrhosis dementia differential differentiation disorder encephalopathy fatty hand hiv hyperammonemia leukostasis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... #APML #diagnosis ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... myeloma, CML, AML ... rare): - Reye syndrome ... (Peds) - Primary ... deficiency #Ammonia #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
• Female:Male 9: ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... or higher • Liver ... diagnosis #workup #hepatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Global mortality: 9- ... survival is 93-95% Pathophysiology ... heart (2-5%), liver ... Sarcoidosis #Diagnosis #Management
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... • Depressive symptoms ... is similar to PML ... The clinical syndrome ... HIV and with low CD4
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Etiology: • Pathophysiology ... Neurological symptoms ... Seizures: Treat with AEDs ... #diagnosis #management
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