10 results
Malaria - Plasmodium Life Cycle
1) Mosquito takes a blood meal (injects sporozoites)
Human Liver Stages
2) Infected liver
sporozoites) Human Liver ... Stages 2) Infected liver ... a blood meal 9) ... lifecycle #diagnosis #pathophysiology ... #infectiousdiseases
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone: • Liver ... lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
• Female:Male 9: ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... or higher • Liver ... diagnosis #workup #hepatology
Schistosoma Life Cycle - Schistosomiasis
1) Eggs shed from infected human: in feces, in urine
2) Eggs hatch
) Circulation 9) ... portal blood in liver ... circulate to the liver ... Schistosomiasis #diagnosis #pathophysiology ... #infectiousdiseases
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Global mortality: 9- ... survival is 93-95% Pathophysiology ... Features: • Many symptoms ... patients have no symptoms ... heart (2-5%), liver
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyophosphatasia #hepatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
acute respiratory symptoms ... Rheumatologic symptoms ... Mississippi and Ohio River ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Common Signs and Symptoms ... - Elevated liver ... Pathophysiology ... Diagnosis #Management #Hematology