10 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... • Female:Male 9: ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... diagnosis #workup #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Tuberculosis Treatment ... INH daily X 6 or 9 ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Tuberculosis Treatment ... INH daily X 6 or 9 ... #Diagnosis #Management ... #Treatment #ActiveTB
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... epilepticus Treatment ... underlying cause • Treatment ... Syndrome #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Females SIGNS/SYMPTOMS ... identified (autoimmune, meds ... , neoplastic) TREATMENT ... Pneumonia #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... , Hep A/B/CMV, TB ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... and the systemic symptoms ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
acute respiratory symptoms ... Rheumatologic symptoms ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management