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management endocrinology hypercalcemia treatment algorithm causes ckd diagnosis differential drugs hyperparathyroidism medications metabolism migraine nephrology neurology pathophysiology preventative prevention prophylaxis
Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease
Challenges With Vitamin ... Ergocalciferol (D2) Cholecalciferol ... amzn.to/34t5DgJ #VitaminD ... Nephrology #Management #Pharmacology ... #Cholecalciferol
Vitamin D Metabolism Fat-soluble vitamin Sources: dermal synthesis and food (dairy products, fish) Active form: calcitriol (1,25-OH Vitamin D) Main
Vitamin D Metabolism ... Fat-soluble vitamin ... ) Active form: calcitriol ... (1,25-OH Vitamin ... pathophysiology #Cholecalciferol
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
PTH: • Elevated Calcitriol ... (1,25 OH Cholecalciferol ... ) - ↑ 250H Cholecalciferol ... - Excess Vitamin ... Intake - ↓ 25OH Cholecalciferol
Migraine - Preventative Treatments • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
Calcium-channel blockers • Calcitonin ... Supplements: Magnesium, Vitamin ... prophylaxis #prevention #pharmacology
Pharmacologic Options for Hypercalcemia Associated with Cancer Rehydration with NS followed by loop diuretics • IV normal
Pharmacologic Options ... Glucocorticoids - Inhibits vitamin ... conversion to calcitriol ... • Calcitonin ... drugs #treatment #pharmacology
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