18 results
Hormonal Regulation of the Blood Calcium concentration

#Calcium #Regulation #Parathyroid #Calcitonin #Calcitriol #PTH #Endocrinology #Pathophysiology #Hormones
Hormonal Regulation ... Calcium #Regulation #Parathyroid ... #Calcitonin #Calcitriol ... #PTH #Endocrinology ... Pathophysiology #Hormones
Hypercalcemia Evaluation Algorithm 

(PTH = parathyroid hormone; PTHrp: parathyroid hormone–related peptide.)

#Hypercalcemia #Evaluation #Algorithm #Diagnosis
Algorithm (PTH ... = parathyroid hormone ... hormone–related ... #Hypercalcemia # ... Evaluation #Algorithm #Diagnosis
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Parathyroid Hormone ... (PTH) Effect in ... Calcium - Net Effect Hypercalcemia ... #Hormone #PTH # ... pathophysiology #endocrinology
Hypocalcemia Evaluation Algorithm 

(PTH = parathyroid hormone.)

#Hypocalcemia #Evaluation #Algorithm #Diagnosis #Differential
Hypocalcemia Evaluation ... Algorithm (PTH ... = parathyroid hormone ... #Hypocalcemia #Evaluation ... #Algorithm #Diagnosis
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Parathyroid hormone–dependent ... hormone–independent ... hormone–related ... thyrotoxicosis, adrenal ... #Endocrinology
Mechanism of malignancy-associated hypercalcemia. Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D; NHL, non-Hodgkin lymphoma; PTH, parathyroid hormone; PTHrP, PTH-related
non-Hodgkin lymphoma; PTH ... , parathyroid hormone ... ; PTHrP, PTH-related ... #Pathophys #Diagnosis ... #Hypercalcemia
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Serum levels of PTH ... activating mutation - Parathyroid ... hormone resistance ... Hyperparathyroidism #Diagnosis ... #Endocrinology
Hypomagnesemia (Serum level < 1.7 mg/dL)
Neuromuscular manifestations 
 • Tremor, tetany, seizures 
 • Weakness
metabolism • Hypocalcemia ... Hypoparathyroidism • Parathyroid ... hormone resistance ... Decreased synthesis of calcitriol ... Signs #Symptoms #Diagnosis
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... Determine whether PTH-dependent ... Assess for other hormonal ... Assess for non-hormonal ... #algorithm #endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... , adrenal, prostate ... (release of calcitriol ... #Causes #endocrinology ... #diagnosis #differential