8 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... - infiltrates (anemia ... , thrombocytopenia ... cutaneous plaques) AML ... lymphoid organs When Cancer
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... 6.8 g/dL), and thrombocytopenia ... bilobed nuclei, fine ... In addition to APL ... Rods #AuerRods #APL
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... SLE • CLL • APLA ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... • Neutropenia, anemia ... , thrombocytopenia ... Transform to DLBCL, PML ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... progression to AML
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... (AML). ... cytopenias and AML ... disease tolerate anemia ... #algorithm #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
• Plasma cell leukemia ... Castleman disease • AL ... ovarian tumors, lung cancers ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... it is often a cancer ... - Cytopenias (anemia ... , thrombocytopenia ... Diagnosis #Management #Hematology