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hematology management leukemia chronic classification hemeonc mds myelodysplastic syndrome workup arteritis common cvid differential disorders fungal gammopathy gca giantcell hemophagocytic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... - infiltrates (anemia ... lymphoid organs When Cancer ... Leukemia (CLL) ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... 5) Symptoms of anemia ... Transformation to large cell ... uw_IMresidency #CLL ... #Leukemia #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... common - T Cell ... ~10% - B-Cell ... Responsive to Treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... factor (GCSF) treatments ... marrow studies Treatment ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment ... #oncology #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Lymphoma or other cancers ... gastric and breast cancer ... Granulomatous lymphocytic ... autoimmune hemolytic anemia
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
the hematologic cancer ... No evidence of anemia ... insufficiency, Anemia ... to the plasma cell ... #diagnosis #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... lymphoma • B cell ... lymphoma • Large B cell ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
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