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diagnosis treatment barre differential guillain amiodarone apml capsulatum cerebritis cns differentiation erythematosus failure gbs guillainbarre hematology histoplasma histoplasmosis hypoxemic hypoxia
Hypoxemic Respiratory Failure - Differential Diagnosis Framework DECREASED INSPIRED OXYGEN • Low PATM Can decrease first part
Hypoxemic Respiratory ... drive due to neurologic ... obesity-hypoventilation syndrome ... , pulmonary AVMs ... hepatopulmonary syndrome
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute respiratory ... symptoms • Rheumatologic ... by culture or serology ... Diagnosis: • Serology ... #Diagnosis #Management
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
cases/100,000 per ... extremity, facial, respiratory ... patients) • Respiratory ... #diagnosis #management ... #treatment #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Infection (sepsis), PE ... APML #diagnosis #management ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
arthralgia, arm/leg ... affects the skin, neurologic ... cognitive impairment, neurologic ... upper and lower respiratory ... Differential #Diagnosis #Rheumatology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... extremity, facial, respiratory ... Guillain #Barre #Syndrome ... #diagnosis #management ... #neurology
Pulmonary Histoplasmosis Quick Facts on Histoplasma capsulatum: • Dimorphic fungi, in yeast phase within the body •
Pulmonary Histoplasmosis ... • Dimorphic fungi ... common endemic fungal ... corticosteroids for respiratory ... capsulatum #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Disease: • 10%-15% Pulmonary ... effusion, INC risk PE ... , Pulmonary amyloidosis ... #Rheumatology # ... Diagnosis #Management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Dose ≥ 400 mg per ... toxicity (e.g., acute respiratory ... distress syndrome ... pneumonia - Pulmonary ... #diagnosis #management
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