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lupus neurology signs symptoms systemic activation ana antinuclear autoantibodies behcet dermatology differential disease evaluation gravis hematology macrophage mas myasthenia myelitis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... Initial screening test ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... Glucocorticoids 5-ASA ... #diagnosis #management ... signs #symptoms #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... suspected, tests ... SLE-SSc-AlM overlap syndromes ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... #management #neurology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... , breast bone, pelvis ... #Rheumatology # ... diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... tissue: Epithelioid cells ... renal failure Clinical ... anterior/posterior MSK ... #Management #Signs
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... ducts Clinical ... phenomenon (16%) MSK ... #Rheumatology # ... Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Pleocytosis > 100 cells ... negative, MOG-IgG test ... #management #neurology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
specific questions to ask ... determine if stress test ... Change in clinical ... medical and surgical management ... stratification #diagnosis
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