23 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... #Hepatology #gastroenterology ... #management #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... Viral Hepatitis ... #hepatology #transaminitis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
- Differential Diagnosis ... Algorithm Malignant ... Non-Malignant • Fatty Liver ... Primary Biliary Cirrhosis ... #Hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #differential #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... , Acute biliary ... #Differential #Diagnosis ... #algorithm #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... viremia or have cirrhosis ... #HBV #Algorithm ... #Treatment #Hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... > 3 mg/dL) or acute ... liver failure ... #HepatitisB #HepBV ... Indications #management #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Algorithm Severe ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology