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differential causes oncology thrombocytosis activation chronic cll dermatology hemolytic leukemia lymphocytic macrophage management mas mds myelodysplasia myelodysplastic petechiae petechial physicalexam
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... effect following treatment ... following EtOH induced thrombocytopenia ... Iron deficiency anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... Schistocytes, thrombocytopenia ... #Algorithm #workup ... #hematology #testing
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... , and thrombocytopenia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... hemostasis: - Thrombocytopenia ... Autoimmune Vasculitis (lupus ... deficiency Work
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... , thrombocytopenia ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... platelet count (thrombocytopenia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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