1901 results
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... that NSAIDs and ACEI ... ACEI/ARB's are often ... ACEIARB #Effects #Nephrology ... #Renal #Pathophysiology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Injury • Pre-Renal ... : NSAIDS, CNI, ACEI ... diagnosis #algorithm #nephrology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Scleroderma Renal ... of Scleroderma Renal ... ) • Initiate ACEi ... uncontrolled with ACEi ... #rheumatology #nephrology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Creatinine • Chronic renal ... Aldosterone • ACEi ... IntercellularShift #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
oxoproline) • Renal ... Renal acidosis ... hyperkalemia (with renal ... ACE-Is and ARBs ... diagnosis #causes #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
ACEI Antihypertensive ... the following ACEIs ... potassium, and renal ... #ACEInhibitor #ACEIs
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi ... post-hypothermia • ↓ Renal ... Excretion: - Renal ... 15 suggests ↓ renal ... Treatment #potassium #nephrology
Lisinopril - ACE inhibitor used for the treatment of hypertension and heart failure. 3rd most prescribed
Lisinopril - ACE ... Prinivil #Qbrelis #ACEI