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rheumatology management differential erythematosus systemic druginduced laboratory arthritis autoantibodies classification clinicopathology comparison dil disorders emergencies hemeonc hemolytic hodgkins leukemia lymphoma
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... NPSLE rare, Malar rash ... Discontinuation of causal ... Evolution: Chronic disease ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... - Hemolytic anemia ... involvement 3% SLE-Related ... Lupusreference #SLE ... #differential #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... smear, HIV/HCV testing ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #Causes #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... • Immunologic Workup ... Positive in 60-80% of cases ... Evolution: Chronic disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... erythematosus (ACLE ... Differential Diagnosis ... Malignancy (e.g. hematologic ... lymphopenia, low PLT • Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... ): SS, SC, SE, Sβ ... #Algorithm #workup ... #hematology #testing
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... (to support a diagnosis ... #diagnosis #testing
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... : Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
lupus cases, drug-dependent ... NPSLE rare, Malar rash ... • Immunologic Workup ... #DIL #rheumatology ... #diagnosis #treatment
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