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rheumatology differential erythematosus management systemic druginduced laboratory anemia arthritis causes clinicopathology comparison dil disorders hemolytic mds mimickers monoclonal myelodysplasia myelodysplastic
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... involvement 3% SLE-Related ... Lupusreference #SLE ... #autoantibodies ... #differential #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... • Immunologic Workup ... months) and of autoantibodies ... Evolution: Chronic disease ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... • Immunologic Workup ... Evolution: Chronic disease ... Erythematosus #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... erythematosus (ACLE ... • Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... Erythematosus #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... ): SS, SC, SE, Sβ ... #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... smear, HIV/HCV testing ... test, ANA (e.g., SLE ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... (to support a diagnosis ... Arthritis #laboratory #workup ... #diagnosis #testing
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
NPSLE rare, Malar rash ... • Immunologic Workup ... months) and of autoantibodies ... #DIL #rheumatology ... #diagnosis #treatment
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
macular Vasculitis) Autoantibodies ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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