10 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Clinical Guidelines ... Alcohol-Associated Hepatitis (AAH ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... erythematosus (ACLE ... : • AIHA 10% • ... Chronic B-cell activation
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... erythematosus [SLE ... thrombocytopenia • Liver ... #Syndrome #Diagnosis ... #Management #Hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... , AIH diagnosis ... Anti-LKM & Anti-ALC ... #Diagnosis #Management ... #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
complex → plt activation ... : • Clinical Suspicion ... Confirmatory test ↑Se ... D/c all heparin ... #Hematology #HemeOnc
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... profile, including liver ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH ... activation ... Diagnosis (Clinical ... Normal kidney ultrasound ... evaluation essential in all
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • In all patients ... Clinical Presentation ... - Elevated liver ... #Management #Hematology