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hematology monoclonal treatment algorithm apml classification clinical criticalcare differentiation encephalopathy foamed gammopathy gap globulin hodgkins hyponatremia lymphoma mds mgus myelodysplasia
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Features: POEMS, AL ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... initiation • Differential ... #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
circulation: MCA ACA ... Reversible course Differential ... Diagnosis: • ... #diagnosis #management ... #neurology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... 3 questions to work ... demyelination syndrome ... #Diagnosis #Treatment ... #management #nephrology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... #oncology #management
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
conditions which all ... hormones that work ... for Refeeding Syndrome ... #diagnosis #differential ... #algorithm #management
Primary Polydipsia Definition: Excessive volitional water intake Epidemiology: • 6-20% of patients with psychiatric disorders - Most commonly
in one study, all ... diabetes insipidus Differential ... Diagnosis: Diabetes ... intoxication Initial Workup ... #management #nephrology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... Castleman disease • AL ... Gap #ProteinGap #differential ... #diagnosis #hematology
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