24 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Lupusreference #druginduced ... comparison #table #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology # ... rheumatology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... spontaneously (before any treatments ... malignancies Treatments ... uric acid > 10 mg/dl ... #Tumor #Lysis #Syndrome
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
thiazidic, PPI, ACE ... constitutional symptoms • Treatment ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... develop leukostasis syndrome ... Fibrinolysis & DIC ... • Tumor lysis syndrome ... #Leukemia #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Treatment: • Corticosteroids ... #Rheumatology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
with suspected DGl ... workup • Test all ... Arthritis-Dermatitis syndrome ... Purulent Arthritis Syndrome ... Distal joints, knees
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... with isolated del ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology