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diagnosis dermatology hematology pulmonary algorithm causes classification cutaneous erythematosus glomerulonephritis hemoptysis lupus management mimics monoclonal nonpalpable oncology palpable paraproteinemias progressive
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... +MPO) • Cryoglobulinemic ... Differential ... Low levels mixed cryoglobulinemia ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm #rheumatology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Syndromes and Mimics - Differential ... glomerulonephritis 90%: - ANCA ... Double Positive (ANCA ... Complement Levels: SLE, Cryoglobulinemic ... differentiation syndrome in APL
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... Urticarial/LCV) - Cryoglobulinemic ... ANCA Associated: ... : • Behcet Disease ... #dermatology #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HSP • Cryoglobulinemia ... (MIXED) • ANCA ... Vasculopathy #Purpura #Differential ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... + MPO) Cryoglobulinemic ... #Differential #Diagnosis ... #Rheumatology
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... Kaposi's sarcoma • Rheumatologic ... / Autoimmune: ANCA-Assoc ... vasculitis (GPA ... > EGPA, MPA), Cryoglobulinemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... (Cryoglobulinemic ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... #Monoclonal #Differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : • 7%, Cryoglobulinemia ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
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